PF-0463481 succinate is a potent and orally active dual CCR2/CCR5 antagonist with comparable human and rodent CCR2 potency (rat IC50=20.8 nM), and displays 10-20 fold less rodent CCR5 potency (rat IC50=470 nM). PF-0463481 succinate is safe and well-tolerated and has the potential for the study of diabetic nephropathy[3].
Molecular Weight:
629.67
Purity:
99.50
CAS Number:
[2140301-98-8]
Formula:
C29H42F3N5O7
Target:
CCR
Application Notes:
MCE Product type: Reference compound
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