PF-06685249 (PF-249) is a potent and orally active allosteric AMPK activator with an EC50 of 12 nM for recombinant AMPK alpha1beta1gamma1. PF-06685249 improves renal function in ZSF-1 rats with diabetic nephropathy. PF-06685249 can be used for diabetic nephropathy research[1].
Molecular Weight:
345.78
Purity:
98.00
CAS Number:
[1467059-70-6]
Formula:
C17H16ClN3O3
Target:
AMPK
Application Notes:
MCE Product type: Reference compound
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