LP-935509 is an orally active, potent, selective, ATP-competitive and brain-penetrant inhibitor of adaptor protein-2 associated kinase 1 (AAK1) with an IC50 of 3.3 nM and a Ki of 0.9 nM, respectively. LP-935509 is also a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 shows antinociceptive activity. LP-935509 can be used for neuropathic pain and SARS-CoV-2 research[1].
Molecular Weight:
396.44
Purity:
99.74
CAS Number:
[1454555-29-3]
Formula:
C20H24N6O3
Target:
AAK1,Cyclin G-associated Kinase (GAK),SARS-CoV
Application Notes:
MCE Product type: Reference compound
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