GSK-114 is a highly selective, orally active TNNI3K inhibitor (IC50= 25 nM). GSK-114 shows a 40-fold selectivity for TNNI3K over B-Raf kinase (IC50= 1 µM). Cardiac troponin I-interacting kinase (TNNI3K or CARK) is a member of the tyrosine-like kinase family that is selectively expressed in heart tissue[1].
Molecular Weight:
417.48
Purity:
99.52
CAS Number:
[1301761-96-5]
Formula:
C19H23N5O4S
Target:
MAP3K
Application Notes:
MCE Product type: Reference compound
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