SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease[1][2][3].
Molecular Weight:
507.51
Purity:
99.25
CAS Number:
[1818389-84-2]
Formula:
C27H24F3N5O2
Target:
SRPK,VEGFR
Application Notes:
MCE Product type: Reference compound
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