EBI-907 is an orally active and highly potent B-RafV600E inhibitor. EBI-907 demonstrates excellent A375 and Colo-205 cellular antiproliferative activity with IC50 values of 13 nM and 14 nM, respectively. EBI-907 can also cause tumor regression in a B-RafV600E-dependent Colo-205 tumor xenograft model of mice. EBI-907 is promising for research of melanoma and B-RafV600E associated cancers[1][2].
Molecular Weight:
506.95
CAS Number:
[1581764-31-9]
Formula:
C23H21ClF2N4O3S
Target:
Raf
Application Notes:
MCE Product type: Reference compound
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