PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and glycine EC50. PYD-106 selectively enhances the responses of diheteromeric GluN1/GluN2C receptors but not triheteromeric GluN1/GluN2A/GluN2C receptors[1].
Molecular Weight:
432.47
Purity:
98.13
CAS Number:
[1560894-05-4]
Formula:
C25H24N2O5
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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