NMS-P645 is a PIM1 inhibitor. NMS-P645 exhibits anti-proliferative activity when combined with GDC-0941 (HY-50094) in TMPRSS2/ERG positive and negative PCa cells. NMS-P645 can reverse PIM1-induced pro-survival signals in prostate cells. NMS-P645 can be studied in research on prostate cancer[1].
Molecular Weight:
512.09
CAS Number:
[1482518-95-5]
Formula:
C28H38ClN5O2
Target:
Pim
Application Notes:
MCE Product type: Reference compound
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