PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14alpha-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 µM and 0.22 µM, respectively[1][2].
Molecular Weight:
682.73
Purity:
99.27
CAS Number:
[1931946-73-4]
Formula:
C38H37F3N6O3
Target:
Cytochrome P450,Fungal
Application Notes:
MCE Product type: Reference compound
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