GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer[1][2].
Molecular Weight:
554.60
Purity:
99
CAS Number:
[13616-29-0]
Formula:
C23H22N8O5S2
Target:
Fatty Acid Synthase (FASN)
Application Notes:
MCE Product type: Reference compound
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