BMS-187308 is an orally active endothelin-A (ETA) antagonist, with Kis of 4.7 nM for ETA and 1.7 µM for ETB. BMS-187308 inhibits the pressor response to ET-1 (ED25: 1.2 µmol/kg, iv). BMS-187308 is a suitable tool for investigating the role of endothelin[1].
Molecular Weight:
399.51
CAS Number:
[153624-15-8]
Formula:
C21H25N3O3S
Target:
Endothelin Receptor
Application Notes:
MCE Product type: Reference compound
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