Fidrisertib (BLU-782) is the orally active inhibitor for activin receptor-like kinase 2 (ALK2) that inhibits ALK2R206H, ALK2, ALK1, ALK6, ALK3, ALK4, TGFbetaR2 and ALK5 with IC50s of 0.2, 0.6, 3, 24, 45, 65, 67 and 155 nM, respectively[1][2].
Molecular Weight:
562.70
Purity:
98.17
CAS Number:
[2141955-96-4]
Formula:
C31H42N6O4
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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