CK-2-68 is an inhibitor for complex III in protozoan mitochondrial respiratory chain, by targeting the alternative NADH dehydrogenase (NDH2) of the malarial parasite Plasmodium. CK-2-68 exhibits antimalaria efficacy, that inhibits Plasmodium falciparum infected erythrocytes with an IC50 of 40 nM[1].
Molecular Weight:
443.85
Purity:
98.91
CAS Number:
[1361004-87-6]
Formula:
C24H17ClF3NO2
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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