SRI-31142 is a putative, brain-penetrant allosteric inhibitor of the dopamine transporter (DAT). In behavioral studies using intracranial self-stimulation (ICSS), SRI-31142 did not produce the abuse-related effects seen with cocaine and GBR-12935, but instead reduced ICSS responses and dopamine levels in the nucleus accumbens (NAc) at effective doses. SRI-31142 also blocked cocaine-induced increases in ICSS and NAc dopamine[1].
Molecular Weight:
456.54
Purity:
99.89
CAS Number:
[1940118-04-6]
Formula:
C29H24N6
Target:
Dopamine Transporter
Application Notes:
MCE Product type: Reference compound
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