NS004 is a potassium (BK) channel activator that increases Iberiotoxin (HY-P0190) or Tetraethylammonium (HY-B1793)-sensitive whole-cell efflux currents. NS004 also significantly increased the activity of individual GH3 cell BK channels and rat brain BK channels reorganized into planar lipid bilayers, causing an increase in channel mean open time, a decrease in intermittent time, and an increase in channel voltage/calcium sensitivity[1].
Molecular Weight:
328.67
Purity:
99.67
CAS Number:
[141797-92-4]
Formula:
C14H8ClF3N2O2
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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