(S)-ML399 (Compound 18S) is the enantiomer of ML399 (HY-117948). (S)-ML399 acts as a Menin-MLL interaction inhibitor with an IC50 of 1400 nM. (S)-ML399 can be used to investigate acute leukemias with MLL translocations, including acute myeloid leukemia and acute lymphoblastic leukemia[1].
Molecular Weight:
445.53
CAS Number:
[1560968-51-5]
Formula:
C27H28FN3O2
Target:
Drug Isomer,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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