BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling.
Molecular Weight:
330.59
Purity:
99.97
CAS Number:
[1374984-75-4]
Formula:
C14H10Cl3NO2
Target:
CXCR,Formyl Peptide Receptor (FPR)
Application Notes:
Reference compound
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