ML356 (Compound 16) is an inhibitor for fatty acid synthase (FAS), that inhibits the thioesterase domain of FAS (FAS TE) with an IC50 of 0.334 µM, and blocks the de novo palmitate synthesis in PC-3 cell with an IC50 of 20 µM. ML356 exhibits good membrane permeability, and good stability in human and mouse plasma[1].
Molecular Weight:
423.55
CAS Number:
[1808260-45-8]
Formula:
C19H25N3O4S2
Target:
Fatty Acid Synthase (FASN)
Application Notes:
MCE Product type: Reference compound
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