PPM-18 (NSC 73233), a potent anti-inflammatory agent, inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-kappaB to promoter[1]. PPM-18, an analog of Vitamin K, induces autophagy and apoptosis in bladder cancer cells through ROS and AMPK signaling pathways[2].
Molecular Weight:
277.27
Purity:
99.17
CAS Number:
[65240-86-0]
Formula:
C17H11NO3
Target:
NO Synthase
Application Notes:
MCE Product type: Reference compound
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