LU-32-176B, a GABA transporter 1(GAT1) selective inhibitor, is found to exert a synergistic anticonvulsant action with GAT2 transport inhibitor EF1502. LU-32-176B inhibits neurons, astrocytes and mGAT1 with the IC50 values of 2µM, 1µM, 4µM, respectively[1][2].
Molecular Weight:
398.45
CAS Number:
[770688-66-9]
Formula:
C23H24F2N2O2
Target:
GABA Receptor
Application Notes:
MCE Product type: Reference compound
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