GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNalpha and TFNalpha. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for asthma[1].
Molecular Weight:
390.52
Purity:
99.79
CAS Number:
[1207629-49-9]
Formula:
C20H34N6O2
Target:
IFNAR,TNF Receptor,Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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