PD130883 is an antifolate DHFR inhibitor that directly inhibits thymidylate synthase at the 5,10-methylenetetrahydrofolate binding site, reducing the net conversion of tetrahydrofolate cofactor to dihydrofolate.
Molecular Weight:
349.34
CAS Number:
[123685-36-9]
Formula:
C18H15N5O3
Target:
Antifolate,Dihydrofolate reductase (DHFR)
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
