IPS-05002 is an alpha5beta1 antagonist. IPS-05002 can inhibit VEGF-stimulated human umbilical vein endothelial cell (HUVEC) proliferation, adhesion, and migration, and also suppresses tubular network formation. IPS-05002 can upregulate IKB-beta, XRCC4, and downregulate Cdc6 in VEGF-induced HUVECs. IPS-05002 can be used for the study of tumor angiogenesis[1].
Molecular Weight:
422.48
CAS Number:
[1185036-77-4]
Formula:
C22H19FN4O2S
Target:
Integrin
Application Notes:
MCE Product type: Reference compound
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