AKN-028 (TFA), CAS [[1175017-91-0]] Preis auf Anfrage

Product Overview

• Article Name: AKN-028 (TFA), CAS [[1175017-91-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-118304A
• Supplier Catalog Number: HY-118304A
• Alternative Catalog Number: MCE-HY-118304A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AKN-028 TFA, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. AKN-028 TFA inhibits FLT3 autophosphorylation. AKN-028 TFA induces dose-dependent cytotoxic response (mean IC50=1 µM). AKN-028 TFA induces apoptosisby activation of caspase 3. AKN-028 TFA can be used in research of acute myeloid leukemia (AML)[1].

Product Properties

• Molecular Weight: 416.36
• CAS Number: [1175017-91-0]
• Formula: C19H15F3N6O2
• Target: Apoptosis,Caspase,FLT3

Application Notes

• Application Notes: MCE Product type: Reference compound