Lu AE51090 is selective muscarinic M1 receptor agonist with blood-brain barrier penetration. Lu AE51090 activates human M1 receptor with EC50 of 61 nM, while showing no significant agonism at M2-M5 receptors. Lu AE51090 exerts procognitive effects in mice. Lu AE51090 can be used for the study of Alzheimers disease (AD) and cognitive impairment associated with schizophrenia (CIAS)[1].
Molecular Weight:
407.51
Purity:
99.51
CAS Number:
[1186229-95-7]
Formula:
C24H29N3O3
Target:
mAChR
Application Notes:
MCE Product type: Reference compound
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