TP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells[1].
Molecular Weight:
298.39
CAS Number:
[864374-00-5]
Formula:
C14H10N4S2
Target:
TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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