JUN-1111 is an irreversible and selective Cdc25 phosphatase inhibitor with IC50 values of 0.38, 1.8, 0.66, 28, 37 µM for Cdc25A, Cdc25B, Cdc25C, VHR, PTP1B, respectively. JUN-1111 induces cell cycle arrest at G1 and G2/M phases. JUN-1111 decreases the expression of phosphoCdk1[1][2].
Molecular Weight:
287.31
Purity:
98.57
CAS Number:
[874351-38-9]
Formula:
C15H17N3O3
Target:
Phosphatase
Application Notes:
MCE Product type: Reference compound
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