N-Desmethyl rosiglitazone (SB 237216) is a metabolite of Rosiglitazone (HY-17386), generated through demethylation by the cytochrome P450 enzyme system in liver microsomes. It retains partial PPARgamma agonist activity and supports studies on the metabolism and pharmacokinetics of Rosiglitazone (HY-17386)[1].
Molecular Weight:
343.40
CAS Number:
[257892-31-2]
Formula:
C17H17N3O3S
Target:
Cytochrome P450,Drug Metabolite,PPAR
Application Notes:
MCE Product type: Reference compound
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