ATM Inhibitor-10 (compound 74), a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors[1].
Molecular Weight:
434.47
Purity:
98.7
CAS Number:
[1941214-06-7]
Formula:
C23H23FN6O2
Target:
ATM/ATR
Application Notes:
MCE Product type: Reference compound
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