NGD9002 (free base), CAS [[666256-06-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-118935
Supplier Catalog Number:
HY-118935
Alternative Catalog Number:
MCE-HY-118935-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
NGD9002 free base is a new generation of selective corticotropin-releasing factor-1 (CRF-1) receptor antagonist with inhibitory activity on CRF-induced colonic function stimulation. NGD9002 free base can reduce CRF-induced fecal output response and show an inhibitory IC50 value of 4.3 mg/kg. NGD9002 free base can effectively block CRF-induced colonic secretory motility stimulation at the highest dose and reduce acute water avoidance-induced defecation. NGD9002 free base can also prevent the occurrence of pain hypersensitivity reactions to repeated colonic distension[1].
Molecular Weight:
357.49
CAS Number:
[666256-06-0]
Formula:
C20H31N5O
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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