Topovale (ARC 111) is a topoisomerase I inhbitor. Topovale is an antitumor agent, and shows low nM cytotoxicity against a panel of cancer cells. Topovale induces reversible topoisomerase I (TOP1) cleavage complexes in tumor cells[1].
Molecular Weight:
421.45
Purity:
99.94
CAS Number:
[500214-53-9]
Formula:
C23H23N3O5
Target:
Topoisomerase
Application Notes:
MCE Product type: Reference compound
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