L-748328 is a potent and selective human beta3-adrenergic receptor antagonist. L-748328 has a Ki of 3.7 nM against human cloned beta3-AR expressed in Chinese hamster ovary (CHO) cells. In addition, L-748328 inhibits the lipolytic response induced by the beta3-AR agonist L-742791 in isolated non-human primate adipocytes[1].
Molecular Weight:
505.61
CAS Number:
[244192-93-6]
Formula:
C23H27N3O6S2
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound1
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