LAF389, a prodrug of LAF153, is a methionine aminopeptidase (MetAps) inhibitor with an IC50 of 800 nM against MetAp2, and exhibits a maximum inhibition rate of 20% against MetAp1 at 300 nM. LAF389 possesses antiproliferative, antiangiogenic and cytotoxic activities. LAF389 can be used in research related to cancers such as advanced solid tumors[1][2].
Molecular Weight:
498.61
CAS Number:
[270902-51-7]
Formula:
C25H42N2O8
Target:
MetAP
Application Notes:
MCE Product type: Reference compound1
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