UK-101 is a potent and selective immunoproteasome beta1i (LMP2) inhibitor with an IC50 value of 104 nM, displays 144- and 10-fold selectivity over beta1c (IC50=15 µM) and beta5 subunit (IC50=1 µM), respectivey[1]. UK-101 induces cell apoptosis and can be used for the study of prostate cancer[2].
Molecular Weight:
484.74
Purity:
99.58
CAS Number:
[1000313-40-5]
Formula:
C25H48N2O5Si
Target:
Apoptosis,Proteasome
Application Notes:
MCE Product type: Reference compound1
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