LY456066 is a selective non-competitive metabotropic glutamate receptors (mGluR1) antagonist with an IC50 value of 52.0 nM. LY456066 is effective in rodent models of anxiolysis and nociception. LY456066 reduces hyperalgesia and the amount of licking and flinching following formalin injection, which is promising for research of analgesics for chronic pain[1][2].
Molecular Weight:
341.47
Purity:
99
CAS Number:
[338738-66-2]
Formula:
C19H23N3OS
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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