AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). AZD-5672 shows moderate activity against the hERG ion channel (binding IC50=7.3 µM). AZD5672 is a substrate of human P-gp, and inhibits P-gp-mediated digoxin transport (IC50=32 µM). AZD-5672 can be used for the research of rheumatoid arthritis[1][2][3].
Molecular Weight:
632.78
Purity:
95.74
CAS Number:
[780750-65-4]
Formula:
C32H38F2N2O5S2
Target:
CCR,P-glycoprotein,Potassium Channel
Application Notes:
MCE Product type: Reference compound
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