LY 379196 is a PKC-beta inhibitor (IC50: 50 nM and 30 nM for PKC betaI and betaII respectively). LY 379196 inhibits the VEGF, IGF-1 and bFGF-induced proliferation of bovine retinal microvascular endothelial cells (BREC). LY 379196 is an antiproliferatory agentfor proliferative retinopathy[1][2].
Molecular Weight:
562.68
Formula:
C30H34N4O5S
Target:
PKC
Application Notes:
MCE Product type: Reference compound
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