CP-664511 is an orally active and potent alpha4beta1 integrin antagonist with anti-inflammatory effects (IC50=0.52 nM). CP-664511 inhibits the interaction between alpha4beta1 and vascular cell adhesion molecule-1 (VCAM-1), significantly reducing eosinophil infiltration into lung tissue. CP-664511 is promising for research of asthma and allergic airway diseases[1].
Molecular Weight:
522.59
CAS Number:
[379692-00-9]
Formula:
C28H34N4O6
Target:
Integrin
Application Notes:
MCE Product type: Reference compound
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