PF-06445974, CAS [[2055776-17-3]]

Product Overview

• Article Name: PF-06445974, CAS [[2055776-17-3]]
• Biozol Catalog Number: MCE-HY-119190
• Supplier Catalog Number: HY-119190
• Alternative Catalog Number: MCE-HY-119190-50MG,MCE-HY-119190-10MMX1ML,MCE-HY-119190-10MG,MCE-HY-119190-25MG,MCE-HY-119190-5MG,MCE-HY-119190-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PF-06445974, a promising positron emission tomography (PET) lead, has exquisite potency at PDE4B with an IC50 50 values are 36, 4.7 and 17 nM for PDE4D, PDE4A and PDE4C, respectively. PF-06445974 has good selectivity over PDE4D, excellent brain permeability, and a high level of specific binding in the cold tracer study[1].

Product Properties

• Molecular Weight: 346.36
• Purity: 98.59
• CAS Number: [2055776-17-3]
• Formula: C20H15FN4O
• Target: Phosphodiesterase (PDE)

Application Notes

• Application Notes: MCE Product type: Reference compound