Caprospinol (SP-233) is a steroid compound candidate based on the structure of 22R-hydroxycholesterol. It has multiple mechanisms of neuroprotection, including binding to beta-amyloid protein (Abeta(42)), interacting with the mitochondrial respiratory chain, clearing Abeta(42) monomers, and acting as a sigma-1 receptor ligand. It can cross the blood-brain barrier in vivo and restore cognitive impairment, and has the potential to inhibit Alzheimers disease.
Molecular Weight:
512.76
CAS Number:
[4952-56-1]
Formula:
C33H52O4
Target:
Amyloid-beta,Sigma Receptor
Application Notes:
MCE Product type: Reference compound
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