Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT2A receptors, and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction[1][2][3].
Molecular Weight:
470.01
Purity:
98.01
CAS Number:
[83366-66-9]
Formula:
C25H32ClN5O2
Target:
5-HT Receptor,Cytochrome P450
Application Notes:
MCE Product type: Reference compound1
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