ABT-100, CAS [[450839-40-4]]
Catalog Number:
MCE-HY-119257
| Article Name: |
ABT-100, CAS [[450839-40-4]] |
| Biozol Catalog Number: |
MCE-HY-119257 |
| Supplier Catalog Number: |
HY-119257 |
| Alternative Catalog Number: |
MCE-HY-119257-5MG |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| ABT-100, a chemical probe, is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity[1]. |
| Molecular Weight: |
504.46 |
| Purity: |
98 |
| CAS Number: |
[450839-40-4] |
| Formula: |
C27H19F3N4O3 |
| Target: |
Apoptosis,Farnesyl Transferase |
| Application Notes: |
MCE Product type: Reference compound |
