CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism[1].
Molecular Weight:
556.40
Purity:
99.11
CAS Number:
[256497-58-2]
Formula:
C27H26BrNO7
Target:
Apoptosis,c-Myc
Application Notes:
MCE Product type: Reference compound
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