Pioglitazone ketone is an active metabolite of the PPARgamma agonist Pioglitazone (HY-13956). Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.
Molecular Weight:
370.42
CAS Number:
[146062-45-5]
Formula:
C19H18N2O4S
Target:
PPAR
Application Notes:
MCE Product type: Reference compound1
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