SAS-0132 is a selective Sigma 2 receptor (Sig2R) antagonist (Ki: 90 nM) that can cross the blood-brain barrier. SAS-0132 is capable of regulating intracellular Ca2+ levels and modulating PGRMC1-related pathways. SAS-0132 exhibits neuroprotective activity and can improve cognitive impairment in Alzheimers disease mice. SAS-0132 can be used in the research of neurocognitive disorders such as Alzheimers disease[1].
Molecular Weight:
391.51
CAS Number:
[1644629-60-6]
Formula:
C24H29N3O2
Target:
Calcium Channel,Sigma Receptor
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
