Acetoxycycloheximide, CAS [[2885-39-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-119420
Supplier Catalog Number:
HY-119420
Alternative Catalog Number:
MCE-HY-119420-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Acetoxycycloheximide is an antibiotic with antitumor activity. Acetoxycycloheximide a protein synthesis inhibitor. Acetoxycycloheximide significantly induces activation of procaspase-3 and subsequent apoptosis mediated by the Cytochrome c from mitochondria via activation of JNK pathway. Acetoxycycloheximide triggers the downregulation of cell surface TNF-R1 via the activation of ERK and p38 MAPK, thereby preventing activation of the NF-kappaB signaling pathway by TNF-alpha. Acetoxycycloheximide is much more toxic to female rats than to males. Acetoxycycloheximide can be used for inflammatory and immune diseases and cancers research[1][2][3].
