Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-alpha and NF-kappaB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic[1][2][3][4][5][6][7][8].
Molecular Weight:
396.71
Purity:
99.76
CAS Number:
[658066-35-4]
Formula:
C16H11ClF6N2O
Target:
Caspase,Constitutive Androstane Receptor,Fungal,NF-kappaB,Parasite,Pregnane X Receptor (PXR),Succinate Dehydrogenase
Application Notes:
MCE Product type: Reference compound
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