MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor gammat (RORgammat) inverse agonists with an IC50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells[1].
Molecular Weight:
444.79
Purity:
99.11
CAS Number:
[1392809-08-3]
Formula:
C22H12ClF3N2O3
Target:
ROR
Application Notes:
MCE Product type: Reference compound
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