(Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the beta-arrestin2 recruitment assay (GS-cAMP, EC50=0.8 nM, beta-arrestin2, EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity[1].
Molecular Weight:
391.34
Purity:
99.87
CAS Number:
[1643462-64-9]
Formula:
C19H16F3N3O3
Target:
Arrestin,Dopamine Receptor
Application Notes:
MCE Product type: Reference compound
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