Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
Molecular Weight:
453.61
Purity:
99.70
CAS Number:
[139893-43-9]
Formula:
C25H43NO6
Target:
HMG-CoA Reductase (HMGCR),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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